Contrave diet pill is a weight loss medicine approved by FDA in 2014. Contrave ingredients bupropion and naltrexone are both showing certain effectiveness in weight loss. Naltrexone is used to treat alcohol and opioid addiction while bupropion is prescribed for patients with depression and mental/mood disorders. The combination of both drugs in an extended-release formulation is expected to have a synergistic effect on hunger suppression. Contrave is prescribed to adults who struggle with obesity, in addition to low-calorie diet and exercise. You should always consult your doctor prior to buying Contrave weight loss drug.

Contrave diet pill is indicated for patients with a BMI index of 25 kg/m2 or greater as a part of a long-term weight-management strategy. BMI (Body mass index) is used to define categories of obesity and overweight, the greater number associated with a greater risk for a health condition. BMI is a widely used tool for preliminary diagnosis, but it is supposed to work on average, physically inactive people. Athletes may have high BMI indexes, but a low percentage of body fat, and could not be considered overweight.

According to the Centers for Disease Control and Prevention, more than 36% of adults in the US are now in the obese category with BMI index more than 30. Another 30% are overweight, with BMI ranging from 25 to 30. Adults with a body mass index greater than 30 kg/m2 are diagnosed with obesity and could include Contrave diet pill in their treatment plan for a full year in order to lose 2-4x more weight during the period. Adults who are overweight (BMI greater than 25 kg/m2) may be prescribed Contrave if they have at least one weight-related disease such as type 2 diabetes, high blood pressure or high levels of cholesterol.

Contrave ingredients affect brain’s reward system, helping to control hunger to keep the weight off. Weight loss lessens health risks associated with obesity, such as cardiovascular diseases, certain types of cancer, stroke and a shorter lifespan. Clinical trials show the effectiveness of Contrave over placebo when both are administered as a part of complex treatment including increased physical activity and a healthier diet. 40% of patients in the Contrave trials had been diagnosed with diabetes type 2, and almost all of them suffered from high blood pressure and hyperlipidemia.

However, sudden change of the harmful lifestyle is by no means a simple task for most of the patients. Our motivation depends on so-called “rewards” received when you feel pleasure and satisfaction. Contrave affects neural structures, responsible for that process. Usually, they are changing quite slowly, and it may be extremely difficult in the beginning to stop the routine action-pleasure cycle centered on food. But the Contrave mechanism of action makes the weight loss process more effective and less stressful to the mind because it makes it easier to control cravings.

Multiple trials in both male and female patients had shown the effectiveness of the Contrave diet pill over placebo. Patients were also prescribed with exercises and a reduced-calorie diet. They were intended to lose at least 5% of their body fat during the one-year trial. Only 17% of them reached the goal with placebo. In the group taking Contrave, the number was considerably higher–42% of patients managed to lose the required minimum amount of weight. Actually, 2/3 of them lost more than 5% of their weight on Contrave.

The slower pace of the weight-loss process may be beneficial for your health, giving your body enough time to adapt to the changes. And each percent is a great improvement, reducing the risks of heart failure. Contrave proved to work well in patients with various health problems, but it also has some contraindications and side effects, and you should always discuss your options with your doctor.

Contraindications of Contrave include uncontrolled high blood pressure and seizures. Patients with heart diseases should take the medicine carefully, monitoring their blood pressure and heart rate at regular intervals during the treatment period. However, studies show that taking Contrave does not increase the risk of heart-related problems in obese patients, even during the long-term treatment.


Contrave ingredients may also cause seizures, so it should not be administered to patients with seizure disorders. The risk is associated with higher doses of the medicine, but if you experience a seizure during the treatment, you should stop taking Contrave completely.

Other medicines may interact with Contrave ingredients so you should always ask your doctor or pharmacist for details. Being an opioid antagonist, naltrexone should not be used with any of the opioid pain medicines or by patients who are in opioid withdrawal. You should also avoid Contrave if you are taking any other medicine containing bupropion, such as Wellbutrin, Aplenzin or Zyban.

Contrave is contraindicated to patients who suffered from eating disorders such as bulimia or anorexia nervosa. Bupropion can influence your mood and provoke suicidal thoughts in patients with depression. Talk to your doctor if you have any concern about Contrave’s effects on your behavior. Refrain from taking the medicine if you drink a lot of alcohol, or just have abruptly stopped drinking. Finally, Contrave weight loss drug should not be prescribed to pregnant or breastfeeding women.

Adults taking Contrave diet pill should evaluate the overall effect of the therapy after 12 weeks. Usually, they should be able to lose at least 5% of their weight (of course, the amount also depends on lifestyle changes). If the therapy didn’t work, it is unlikely that patient would be able to lose more weight with Contrave in the future. In this case, the medicine administration may be discontinued in favor of other forms of treatment.

Contrave mechanism of action was proved safe for adults, but the medicine should not be administered to children and adolescents under the age of 18. And do not forget, that Contrave is a federally controlled substance, only available with a prescription, so do not give or sell your medicine to other people. Uncontrolled use may be ineffective and even may cause irreversible damage to one’s health.